Entity Details

Primary name SLFN14
Entity type gene
Source Source Link

Details

PrimaryID342618
RefseqGeneNG_051181
SymbolSLFN14
Nameschlafen family member 14
Chromosome17
Location17q12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2003-03-28
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSLN14_HUMAN

GO terms

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GOName
GO:0004521 endoribonuclease activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006402 mRNA catabolic process
GO:0016075 rRNA catabolic process
GO:0036345 platelet maturation
GO:0043022 ribosome binding
GO:0071286 cellular response to magnesium ion
GO:0071287 cellular response to manganese ion
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic

Diseases

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Disease IDSourceNameDescription
616913 OMIMBleeding disorder, platelet-type 20 (BDPLT20)A disorder characterized by increased bleeding tendency due to platelet dysfunction. Clinical features include epistaxis, hematomas, bleeding after tooth extraction, and menorrhagia. BDPLT20 is characterized by moderate thrombocytopenia and platelet secretion defects. Inheritance is autosomal dominant. The disease is caused by variants affecting the gene represented in this entry.

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SLFN14S100A10BioGRID, IntAct30021884 details