Entity Details

Primary name SF3B3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15393
EntryNameSF3B3_HUMAN
FullNameSplicing factor 3B subunit 3
TaxID9606
Evidenceevidence at protein level
Length1217
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesSF3B3

GO terms

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GOName
GO:0000375 RNA splicing, via transesterification reactions
GO:0000398 mRNA splicing, via spliceosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005686 U2 snRNP
GO:0005689 U12-type spliceosomal complex
GO:0005730 nucleolus
GO:0008380 RNA splicing
GO:0030620 U2 snRNA binding
GO:0042177 negative regulation of protein catabolic process
GO:0044877 protein-containing complex binding
GO:0071005 U2-type precatalytic spliceosome
GO:0071013 catalytic step 2 spliceosome

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR004871 Cleavage/polyadenylation specificity factor, A subunit, C-terminalDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR018846 Cleavage/polyadenylation specificity factor, A subunit, N-terminalDomainDomain
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04216 QuercetinDrugbanksmall molecule

Interactions

81 interactions

InteractorPartnerSourcesPublicationsLink
SF3B3_HUMANNOL12_HUMANHPRD, IntAct16169070 details
SF3B3_HUMANMPP3_HUMANHPRD, IntAct16169070 details
SF3B3_HUMANWWOX_HUMANBioGRID, MINT16055720 details
SF3B3_HUMANWBP4_HUMANBioGRID, MINT16055720 details
SF3B3_HUMANRBM6_HUMANBioGRID, IntAct21988832 details
SF3B3_HUMANEPS8_HUMANBioGRID, IntAct21988832 details
SF3B3_HUMANKLF10_HUMANBioGRID, MINT21900206 details
SF3B3_HUMANNAGK_HUMANBioGRID, MINT21900206 details
SF3B3_HUMANOSGEP_HUMANBioGRID, MINT21900206 details
SF3B3_HUMANRAD9A_HUMANBioGRID, MINT21900206 details
SF3B3_HUMANRUFY2_HUMANBioGRID, MINT21900206 details
SF3B3_HUMANZN579_HUMANBioGRID, MINT21900206 details
SF3B3_HUMANSMAD5_HUMANBioGRID, MINT21900206 details
SF3B3_HUMANU5S1_HUMANBioGRID, MINT22365833 22939629 28515276 details
SF3B3_HUMANPPIL1_HUMANBioGRID, MINT22365833 details
SF3B3_HUMANHSPB1_HUMANBioGRID, MINT22365833 details
SF3B3_HUMANTOE1_HUMANBioGRID, MINT22365833 details
SF3B3_HUMANZN830_HUMANDIP25599396 details
SF3B3_HUMANISY1_HUMANBioGRID, DIP25599396 26344197 details
SF3B3_HUMANPHF5A_HUMANBioGRID, MINT22939629 24981860 26344197 27720643 details
SF3B3_HUMANCASP6_HUMANIntAct32814053 details
SF3B3_HUMANHIP1_HUMANIntAct32814053 details
SF3B3_HUMANPRKN_HUMANIntAct32814053 details
SF3B3_HUMANVHL_HUMANIntAct32814053 details
SF3B3_HUMANSODC_HUMANIntAct32814053 details
SF3B3_HUMANHD_HUMANIntAct32814053 details
SF3B3_HUMANATX1_HUMANIntAct32814053 details
SF3B3_HUMANTADBP_HUMANIntAct32814053 details
SF3B3_HUMANHGS_HUMANBioGRID19019082 details
SF3B3_HUMANSREK1_HUMANBioGRID, HPRD14559993 details
SF3B3_HUMANSF3B6_HUMANBioGRID22939629 24981860 26344197 27720643 details
SF3B3_HUMANU520_HUMANBioGRID22939629 25849387 details
SF3B3_HUMANTCRG1_HUMANBioGRID16055720 22939629 details
SF3B3_HUMANU2AF2_HUMANBioGRID22939629 26641092 27720643 details
SF3B3_HUMANPR40A_HUMANBioGRID16055720 details
SF3B3_HUMANAPBB1_HUMANBioGRID16055720 details
SF3B3_HUMANERG_HUMANBioGRID24591637 details
SF3B3_HUMANERPG3_HUMANBioGRID31722399 details
SF3B3_HUMANERCC6_HUMANBioGRID31722399 details
SF3B3_HUMANHCK_HUMANHPRD, MINT12029088 details
SF3B3_HUMAN1433G_HUMANBioGRID, HPRD, IntAct, MINT15324660 17353931 details
SF3B3_HUMANRSMN_HUMANIntAct17353931 details
SF3B3_HUMANDEGS1_HUMANIntAct17353931 details
SF3B3_HUMAN1433Z_HUMANMINT15161933 details
SF3B3_HUMANSF3A2_HUMANBioGRID, MINT12234937 17332742 22939629 26344197 details
SF3B3_HUMANSF3B1_HUMANBioGRID, HPRD, MINT10490618 11406595 12234937 21981285 22939629 24981860 26344197 28541300 details
SF3B3_HUMANHS90B_HUMANIntAct22939624 details
SF3B3_HUMANCUL1_HUMANBioGRID, IntAct21145461 23951410 details
SF3B3_HUMANCUL2_HUMANBioGRID, IntAct21145461 23951410 details
SF3B3_HUMANCUL3_HUMANBioGRID, IntAct21145461 23951410 details
SF3B3_HUMANNUDC3_HUMANBioGRID, IntAct25036637 details
SF3B3_HUMANPLK1_HUMANBioGRID, IntAct27173435 unassigned1312 details
SF3B3_HUMANSF3B2_HUMANBioGRID10490618 22939629 26344197 details
SF3B3_HUMANSUPT3_HUMANBioGRID11406595 11564863 details
SF3B3_HUMANTAF9_HUMANBioGRID, HPRD11564863 details
SF3B3_HUMANSRRM1_HUMANBioGRID16159877 details
SF3B3_HUMANSRRM2_HUMANBioGRID16159877 22939629 details
SF3B3_HUMANKAT2A_HUMANBioGRID20946988 31753913 details
SF3B3_HUMANHDAC5_HUMANBioGRID21081666 details
SF3B3_HUMANTOP1_HUMANBioGRID15848144 details
SF3B3_HUMANSMRCD_HUMANBioGRID21549307 details
SF3B3_HUMANTAF10_HUMANBioGRID12601814 details
SF3B3_HUMANSF3B5_HUMANBioGRID22939629 24981860 26344197 27720643 details
SF3B3_HUMANSMC1A_HUMANBioGRID22939629 26344197 31010829 details
SF3B3_HUMANHS90A_HUMANBioGRID22939624 details
SF3B3_HUMANSKP1_HUMANBioGRID23951410 details
SF3B3_HUMANSKP2_HUMANBioGRID23951410 details
SF3B3_HUMANCUL4A_HUMANBioGRID23951410 details
SF3B3_HUMANSMC3_HUMANBioGRID26344197 31010829 details
SF3B3_HUMANTAF4_HUMANBioGRID11406595 details
SF3B3_HUMANAIRE_HUMANBioGRID27365398 details
SF3B3_HUMANFLCN_HUMANBioGRID27353360 details
SF3B3_HUMANCDCA5_HUMANBioGRID31010829 details
SF3B3_HUMANSCC4_HUMANBioGRID31010829 details
SF3B3_HUMANRAD21_HUMANBioGRID31010829 details
SF3B3_HUMANSTAG1_HUMANBioGRID31010829 details
SF3B3_HUMANSTAG2_HUMANBioGRID31010829 details
SF3B3_HUMANWAPL_HUMANBioGRID31010829 details
SF3B3_HUMANPDS5A_HUMANBioGRID31010829 details
SF3B3_HUMANNIPBL_HUMANBioGRID31010829 details
SF3B3_HUMANISG15_HUMANBioGRID33024031 details