Entity Details

Primary name SIX6
Entity type gene
Source Source Link

Details

PrimaryID4990
RefseqGeneNG_008203
SymbolSIX6
NameSIX homeobox 6
Chromosome14
Location14q23.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSIX6_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001654 eye development
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007601 visual perception
GO:0009887 animal organ morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Disease IDSourceNameDescription
212550 OMIMOptic disk anomalies with retinal and/or macular dystrophy (ODRMD)An ocular disorder characterized by optic nerve dysplasia, optic disk anomalies, chorioretinal dystrophy and macular atrophy. Some patients have microphthalmia. The disease is caused by variants affecting the gene represented in this entry.

Interactions

9 interactions