Entity Details

Primary name PALLD_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WX93
EntryNamePALLD_HUMAN
FullNamePalladin
TaxID9606
Evidenceevidence at protein level
Length1383
SequenceStatuscomplete
DateCreated2007-09-11
DateModified2021-06-02

Ontological Relatives

GenesPALLD

GO terms

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GOName
GO:0001725 stress fiber
GO:0001726 ruffle
GO:0002102 podosome
GO:0003334 keratinocyte development
GO:0003382 epithelial cell morphogenesis
GO:0003779 actin binding
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0007010 cytoskeleton organization
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007411 axon guidance
GO:0015629 actin cytoskeleton
GO:0016477 cell migration
GO:0030018 Z disc
GO:0030027 lamellipodium
GO:0030036 actin cytoskeleton organization
GO:0030424 axon
GO:0030426 growth cone
GO:0051371 muscle alpha-actinin binding
GO:0060076 excitatory synapse
GO:0070593 dendrite self-avoidance
GO:0098632 cell-cell adhesion mediator activity

Subcellular Location

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Subcellular Location
Cell junction
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR033017 Palladin, C-terminal immunoglobulin-like domainDomainDomain
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
606856 OMIMPancreatic cancer 1 (PNCA1)A malignant neoplasm of the pancreas. Tumors can arise from both the exocrine and endocrine portions of the pancreas, but 95% of them develop from the exocrine portion, including the ductal epithelium, acinar cells, connective tissue, and lymphatic tissue. Disease susceptibility is associated with variants affecting the gene represented in this entry.