Entity Details

Primary name SLIK1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96PX8
EntryNameSLIK1_HUMAN
FullNameSLIT and NTRK-like protein 1
TaxID9606
Evidenceevidence at protein level
Length696
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesSLITRK1

GO terms

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GOName
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0007409 axonogenesis
GO:0007416 synapse assembly
GO:0030534 adult behavior
GO:0035264 multicellular organism growth
GO:0042592 homeostatic process
GO:0045202 synapse
GO:0050772 positive regulation of axonogenesis
GO:0051965 positive regulation of synapse assembly
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse
GO:0099061 integral component of postsynaptic density membrane
GO:0099560 synaptic membrane adhesion
GO:1905606 regulation of presynapse assembly

Subcellular Location

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Subcellular Location
Cell junction
Membrane
Secreted

Domains

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DomainNameCategoryType
IPR000483 Cysteine-rich flanking region, C-terminalDomainDomain
IPR001611 Leucine-rich repeatRepeatRepeat
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR043326 Slitrk familyFamilyFamily

Diseases

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Disease IDSourceNameDescription
613229 OMIMTrichotillomania (TTM)A neuropsychiatric disorder characterized by chronic, repetitive, or compulsive hair pulling resulting in noticeable hair loss. Affected individuals may develop physical complications and often have overlapping psychological disorders, such as Gilles de la Tourette syndrome or obsessive-compulsive disorder. The disease may be caused by variants affecting the gene represented in this entry.