Entity Details

Primary name TIA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP31483
EntryNameTIA1_HUMAN
FullNameNucleolysin TIA-1 isoform p40
TaxID9606
Evidenceevidence at protein level
Length386
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesTIA1

GO terms

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GOName
GO:0001818 negative regulation of cytokine production
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0008143 poly(A) binding
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010494 cytoplasmic stress granule
GO:0017148 negative regulation of translation
GO:0035925 mRNA 3'-UTR AU-rich region binding
GO:0048024 regulation of mRNA splicing, via spliceosome
GO:0097165 nuclear stress granule
GO:1903608 protein localization to cytoplasmic stress granule
GO:1904037 positive regulation of epithelial cell apoptotic process
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR003954 RNA recognition motif domain, eukaryoteDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR034830 TIA-1, RNA recognition motif 2DomainDomain
IPR034832 TIA-1, RNA recognition motif 3DomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

43 interactions

InteractorPartnerSourcesPublicationsLink
TIA1_HUMANWBP4_HUMANBioGRID, IntAct28838205 details
TIA1_HUMANRU1C_HUMANIntAct12486009 details
TIA1_HUMANFASTK_HUMANBioGRID, HPRD7544399 details
TIA1_HUMANTAU_HUMANBioGRID27160897 27460788 details
TIA1_HUMANTOB1_HUMANUniProt18377426 details
TIA1_HUMANRC3H2_HUMANBioGRID, MINT20412057 29395067 details
TIA1_HUMANDCP1A_HUMANHPIDb, MINT20412057 24965446 details
TIA1_HUMANSND1_HUMANMINT20643132 details
TIA1_HUMANHABP4_HUMANMINT21771594 details
TIA1_HUMANDDX3X_HUMANUniProt18596238 details
TIA1_HUMANPAIRB_HUMANMINT24205981 details
TIA1_HUMANSF01_HUMANIntAct26420826 details
TIA1_HUMANYBOX1_HUMANHPIDb24965446 details
TIA1_HUMANSNRPA_HUMANIntAct12486009 details
TIA1_HUMANRU17_HUMANIntAct12486009 details
TIA1_HUMANPARK7_HUMANMINT29675578 details
TIA1_HUMANRICTR_HUMANBioGRID17461779 details
TIA1_HUMANSRSF3_HUMANBioGRID22939629 27381497 details
TIA1_HUMANWDR6_HUMANBioGRID19910486 details
TIA1_HUMANUBQL2_HUMANBioGRID30442662 details
TIA1_HUMANANXA7_HUMANBioGRID25461769 details
TIA1_HUMANTRI25_HUMANBioGRID31710640 details
TIA1_HUMAN4ET_HUMANBioGRID29395067 details
TIA1_HUMANFUBP3_HUMANBioGRID29395067 details
TIA1_HUMANRAVR1_HUMANBioGRID29395067 details
TIA1_HUMANSMN_HUMANBioGRID29395067 details
TIA1_HUMANTDRD3_HUMANBioGRID29395067 details
TIA1_HUMANUBP11_HUMANBioGRID29395067 details
TIA1_HUMANDDX20_HUMANBioGRID29395067 details
TIA1_HUMANGORS2_HUMANBioGRID29395067 details
TIA1_HUMANRBM20_HUMANBioGRID29395067 details
TIA1_HUMANTOP3B_HUMANBioGRID29395067 details
TIA1_HUMANTXNL1_HUMANBioGRID29395067 details
TIA1_HUMANRENT1_HUMANBioGRID29395067 details
TIA1_HUMANGEMI4_HUMANBioGRID29395067 details
TIA1_HUMANR3HD1_HUMANBioGRID29395067 details
TIA1_HUMANALG13_HUMANBioGRID29395067 details
TIA1_HUMANKCD12_HUMANBioGRID29395067 details
TIA1_HUMANMOONR_HUMANBioGRID29395067 details
TIA1_HUMANKDIS_HUMANBioGRID29395067 details
TIA1_HUMANOTUD4_HUMANBioGRID29395067 details
TIA1_HUMANRBM33_HUMANBioGRID29395067 details
TIA1_HUMANWDCP_HUMANBioGRID29395067 details