Entity Details

Primary name SEM5A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13591
EntryNameSEM5A_HUMAN
FullNameSemaphorin-5A
TaxID9606
Evidenceevidence at protein level
Length1074
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesSEMA5A

GO terms

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GOName
GO:0001755 neural crest cell migration
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO:0005886 plasma membrane
GO:0007155 cell adhesion
GO:0007162 negative regulation of cell adhesion
GO:0007267 cell-cell signaling
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0007413 axonal fasciculation
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0021536 diencephalon development
GO:0030215 semaphorin receptor binding
GO:0030335 positive regulation of cell migration
GO:0030836 positive regulation of actin filament depolymerization
GO:0035373 chondroitin sulfate proteoglycan binding
GO:0043395 heparan sulfate proteoglycan binding
GO:0045499 chemorepellent activity
GO:0045545 syndecan binding
GO:0045766 positive regulation of angiogenesis
GO:0048675 axon extension
GO:0048842 positive regulation of axon extension involved in axon guidance
GO:0048843 negative regulation of axon extension involved in axon guidance
GO:0050918 positive chemotaxis
GO:0051897 positive regulation of protein kinase B signaling
GO:0060326 cell chemotaxis
GO:0070062 extracellular exosome
GO:0071526 semaphorin-plexin signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1990256 signal clustering
GO:2000352 negative regulation of endothelial cell apoptotic process
GO:2001028 positive regulation of endothelial cell chemotaxis

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR001627 Sema domainDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016201 PSI domainDomainDomain
IPR027231 SemaphorinFamilyFamily
IPR036352 Sema domain superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR042821 Semaphorin-5A, sema domainDomainDomain

Diseases

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Interactions

0 interactions

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