Entity Details

Primary name FGF20
Entity type gene
Source Source Link

Details

PrimaryID26281
RefseqGeneNG_015978
SymbolFGF20
Namefibroblast growth factor 20
Chromosome8
Location8p22
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-23
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsFGF20_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001934 positive regulation of protein phosphorylation
GO:0005102 signaling receptor binding
GO:0005104 fibroblast growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009887 animal organ morphogenesis
GO:0010628 positive regulation of gene expression
GO:0014059 regulation of dopamine secretion
GO:0030154 cell differentiation
GO:0030334 regulation of cell migration
GO:0043395 heparan sulfate proteoglycan binding
GO:0043524 negative regulation of neuron apoptotic process
GO:0051897 positive regulation of protein kinase B signaling
GO:0060043 regulation of cardiac muscle cell proliferation
GO:0060113 inner ear receptor cell differentiation
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0090722 receptor-receptor interaction
GO:1904340 positive regulation of dopaminergic neuron differentiation

Diseases

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Disease IDSourceNameDescription
615721 OMIMRenal hypodysplasia/aplasia 2 (RHDA2)A perinatally lethal renal disease encompassing a spectrum of kidney development defects, including renal agenesis, bilateral renal aplasia, hypoplasia, (cystic) dysplasia, and severe obstructive uropathy. The disease is caused by variants affecting the gene represented in this entry.

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
FGF20PTX3BioGRID25912421 details
FGF20FGF9BioGRID, IntAct28514442 details