Entity Details

Primary name SLC30A10
Entity type gene
Source Source Link

Details

PrimaryID55532
RefseqGeneNG_032153
SymbolSLC30A10
Namesolute carrier family 30 member 10
Chromosome1
Location1q41
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-07-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsZNT10_HUMAN

GO terms

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GOName
GO:0005385 zinc ion transmembrane transporter activity
GO:0005769 early endosome
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006828 manganese ion transport
GO:0006882 cellular zinc ion homeostasis
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0010312 detoxification of zinc ion
GO:0016021 integral component of membrane
GO:0043524 negative regulation of neuron apoptotic process
GO:0055037 recycling endosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071421 manganese ion transmembrane transport
GO:0071577 zinc ion transmembrane transport
GO:0071579 regulation of zinc ion transport
GO:1903427 negative regulation of reactive oxygen species biosynthetic process
GO:1904385 cellular response to angiotensin
GO:1905802 regulation of cellular response to manganese ion
GO:2000773 negative regulation of cellular senescence

Diseases

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Disease IDSourceNameDescription
613280 OMIMHypermanganesemia with dystonia 1 (HMNDYT1)A metabolic autosomal recessive disorder characterized by dystonia, parkinsonism, extrapyramidal signs, severe hypermanganesemia, polycythemia, and chronic hepatic disease, including steatosis and cirrhosis. The disease is caused by variants affecting the gene represented in this entry.

Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
SLC30A10SLC30A3BioGRID, UniProt26728129 details
SLC30A10SLC30A10BioGRID, UniProt26728129 details
SLC30A10SLC30A4BioGRID, UniProt26728129 details
SLC30A10SLC30A2BioGRID, UniProt26728129 details
SLC30A10TFRCBioGRID, UniProt26728129 details
SLC30A10SYPBioGRID26728129 details