Entity Details

Primary name IQEC1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6DN90
EntryNameIQEC1_HUMAN
FullNameIQ motif and SEC7 domain-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length963
SequenceStatuscomplete
DateCreated2006-07-11
DateModified2021-06-02

Ontological Relatives

GenesIQSEC1

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005730 nucleolus
GO:0008021 synaptic vesicle
GO:0008289 lipid binding
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0030036 actin cytoskeleton organization
GO:0032012 regulation of ARF protein signal transduction
GO:0043231 intracellular membrane-bounded organelle
GO:0043547 positive regulation of GTPase activity
GO:0051549 positive regulation of keratinocyte migration
GO:0060996 dendritic spine development
GO:0120183 positive regulation of focal adhesion disassembly

Subcellular Location

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Subcellular Location
Cell junction
Cytoplasm
Cytoplasmic vesicle
Nucleus

Domains

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DomainNameCategoryType
IPR000048 IQ motif, EF-hand binding siteSiteBinding site
IPR000904 Sec7 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR023394 Sec7, C-terminal domain superfamilyFamilyHomologous superfamily
IPR030737 IQ motif and SEC7 domain-containing protein 1FamilyFamily
IPR033742 IQ motif and SEC7 domain-containing protein, PH domainDomainDomain
IPR035999 Sec7 domain superfamilyFamilyHomologous superfamily

Diseases

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