Entity Details

Primary name GFRAL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6UXV0
EntryNameGFRAL_HUMAN
FullNameGDNF family receptor alpha-like
TaxID9606
Evidenceevidence at protein level
Length394
SequenceStatuscomplete
DateCreated2006-06-13
DateModified2021-06-02

Ontological Relatives

GenesGFRAL

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0002023 reduction of food intake in response to dietary excess
GO:0007399 nervous system development
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0016167 glial cell-derived neurotrophic factor receptor activity
GO:0030971 receptor tyrosine kinase binding
GO:0031098 stress-activated protein kinase signaling cascade
GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway
GO:0038023 signaling receptor activity
GO:0043235 receptor complex
GO:0043410 positive regulation of MAPK cascade
GO:0043524 negative regulation of neuron apoptotic process
GO:0051897 positive regulation of protein kinase B signaling
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003438 Glial cell line-derived neurotrophic factor receptorFamilyFamily
IPR016017 GDNF/GAS1DomainDomain
IPR037193 GDNF receptor alphaFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink