Entity Details

Primary name VRK2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86Y07
EntryNameVRK2_HUMAN
FullNameSerine/threonine-protein kinase VRK2
TaxID9606
Evidenceevidence at protein level
Length508
SequenceStatuscomplete
DateCreated2003-10-10
DateModified2021-06-02

Ontological Relatives

GenesVRK2

GO terms

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GOName
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006468 protein phosphorylation
GO:0016021 integral component of membrane
GO:0016032 viral process
GO:0018105 peptidyl-serine phosphorylation
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0031966 mitochondrial membrane
GO:0032991 protein-containing complex
GO:0034599 cellular response to oxidative stress
GO:0043408 regulation of MAPK cascade
GO:0046777 protein autophosphorylation
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000659 regulation of interleukin-1-mediated signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum membrane
Mitochondrion membrane
Nucleus
Nucleus envelope

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily

Diseases

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