Entity Details

Primary name MFN1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IWA4
EntryNameMFN1_HUMAN
FullNameMitofusin-1
TaxID9606
Evidenceevidence at protein level
Length741
SequenceStatuscomplete
DateCreated2004-05-24
DateModified2021-06-02

Ontological Relatives

GenesMFN1

GO terms

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GOName
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0008053 mitochondrial fusion
GO:0010918 positive regulation of mitochondrial membrane potential
GO:0016021 integral component of membrane
GO:0016236 macroautophagy
GO:0031306 intrinsic component of mitochondrial outer membrane
GO:0031307 integral component of mitochondrial outer membrane
GO:0042802 identical protein binding
GO:0046039 GTP metabolic process
GO:0051646 mitochondrion localization
GO:0098799 outer mitochondrial membrane protein complex
GO:1990613 mitochondrial membrane fusion

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion outer membrane

Domains

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DomainNameCategoryType
IPR006884 Fzo/mitofusin HR2 domainDomainDomain
IPR022812 DynaminFamilyFamily
IPR027088 Mitofusin-1FamilyFamily
IPR027094 Mitofusin familyFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR030381 Dynamin-type guanine nucleotide-binding (G) domainDomainDomain

Diseases

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