Entity Details

Primary name SETD6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TBK2
EntryNameSETD6_HUMAN
FullNameN-lysine methyltransferase SETD6
TaxID9606
Evidenceevidence at protein level
Length473
SequenceStatuscomplete
DateCreated2007-04-03
DateModified2021-06-02

Ontological Relatives

GenesSETD6

GO terms

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GOName
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0016279 protein-lysine N-methyltransferase activity
GO:0018026 peptidyl-lysine monomethylation
GO:0019827 stem cell population maintenance
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0034968 histone lysine methylation
GO:0048863 stem cell differentiation
GO:0050727 regulation of inflammatory response
GO:0051059 NF-kappaB binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001214 SET domainDomainDomain
IPR011383 N-lysine methyltransferase SETD6FamilyFamily
IPR015353 Rubisco LSMT, substrate-binding domainDomainDomain
IPR036464 Rubisco LSMT, substrate-binding domain superfamilyFamilyHomologous superfamily
IPR044430 SETD6, SET domainDomainDomain

Diseases

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Interactions

4 interactions