Entity Details

Primary name SPPL3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TCT6
EntryNameSPPL3_HUMAN
FullNameSignal peptide peptidase-like 3
TaxID9606
Evidenceevidence at protein level
Length384
SequenceStatuscomplete
DateCreated2002-11-08
DateModified2021-06-02

Ontological Relatives

GenesSPPL3

GO terms

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GOName
GO:0005791 rough endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006465 signal peptide processing
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0016020 membrane
GO:0030660 Golgi-associated vesicle membrane
GO:0032092 positive regulation of protein binding
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0033619 membrane protein proteolysis
GO:0035307 positive regulation of protein dephosphorylation
GO:0042500 aspartic endopeptidase activity, intramembrane cleaving
GO:0042803 protein homodimerization activity
GO:0043231 intracellular membrane-bounded organelle
GO:0050852 T cell receptor signaling pathway
GO:0070886 positive regulation of calcineurin-NFAT signaling cascade
GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Golgi apparatus
Membrane

Domains

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DomainNameCategoryType
IPR006639 Presenilin/signal peptide peptidaseFamilyFamily
IPR007369 Peptidase A22B, signal peptide peptidaseFamilyFamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink