Entity Details

Primary name PDXK_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00764
EntryNamePDXK_HUMAN
FullNamePyridoxal kinase
TaxID9606
Evidenceevidence at protein level
Length312
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesPDXK

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0008270 zinc ion binding
GO:0008478 pyridoxal kinase activity
GO:0009443 pyridoxal 5'-phosphate salvage
GO:0030170 pyridoxal phosphate binding
GO:0030955 potassium ion binding
GO:0031402 sodium ion binding
GO:0031403 lithium ion binding
GO:0034774 secretory granule lumen
GO:0035580 specific granule lumen
GO:0042803 protein homodimerization activity
GO:0042816 vitamin B6 metabolic process
GO:0043312 neutrophil degranulation
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR004625 Pyridoxine kinaseFamilyFamily
IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinaseDomainDomain
IPR029056 Ribokinase-likeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00147 PyridoxalDrugbanksmall molecule
DB00165 PyridoxineDrugbanksmall molecule
DB03909 Adenosine-5'-[Beta, Gamma-Methylene]TriphosphateDrugbanksmall molecule
DB04770 O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OLDrugbanksmall molecule
DB04776 (2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-olDrugbanksmall molecule