Entity Details
| Primary name |
NALP7_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q8WX94 |
| EntryName | NALP7_HUMAN |
| FullName | NACHT, LRR and PYD domains-containing protein 7 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 980 |
| SequenceStatus | complete |
| DateCreated | 2002-10-19 |
| DateModified | 2021-06-02 |
GO terms
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| GO | Name |
| GO:0005524 | ATP binding |
| GO:0010955 | negative regulation of protein processing |
| GO:0019828 | aspartic-type endopeptidase inhibitor activity |
| GO:0019966 | interleukin-1 binding |
| GO:0032691 | negative regulation of interleukin-1 beta production |
| GO:0042802 | identical protein binding |
| GO:0071222 | cellular response to lipopolysaccharide |
| GO:0071347 | cellular response to interleukin-1 |
| GO:0089720 | caspase binding |
| GO:1900016 | negative regulation of cytokine production involved in inflammatory response |
| GO:1905246 | negative regulation of aspartic-type peptidase activity |
Subcellular Location
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Domains
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| Domain | Name | Category | Type |
| IPR004020 | DAPIN domain | Domain | Domain |
| IPR007111 | NACHT nucleoside triphosphatase | Domain | Domain |
| IPR011029 | Death-like domain superfamily | Family | Homologous superfamily |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Family | Homologous superfamily |
| IPR032675 | Leucine-rich repeat domain superfamily | Family | Homologous superfamily |
| IPR041075 | NOD2, winged helix domain | Domain | Domain |
| IPR041267 | NACHT, LRR and PYD domains-containing protein, helical domain HD2 | Domain | Domain |
Interactions
4 interactions