Entity Details

Primary name ARAP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WZ64
EntryNameARAP2_HUMAN
FullNameArf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2
TaxID9606
Evidenceevidence at protein level
Length1704
SequenceStatuscomplete
DateCreated2005-08-16
DateModified2021-06-02

Ontological Relatives

GenesARAP2

GO terms

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GOName
GO:0005096 GTPase activator activity
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0046872 metal ion binding
GO:0051056 regulation of small GTPase mediated signal transduction

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000159 Ras-associating (RA) domainDomainDomain
IPR000198 Rho GTPase-activating protein domainDomainDomain
IPR001164 Arf GTPase activating proteinDomainDomain
IPR001660 Sterile alpha motif domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR037278 ARFGAP/RecO-like zinc fingerFamilyHomologous superfamily
IPR037858 ARAP, RhoGAP domainDomainDomain
IPR038508 ArfGAP domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions