Entity Details

Primary name DHB8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92506
EntryNameDHB8_HUMAN
FullName(3R)-3-hydroxyacyl-CoA dehydrogenase
TaxID9606
Evidenceevidence at protein level
Length261
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesHSD17B8

GO terms

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GOName
GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0005740 mitochondrial envelope
GO:0005759 mitochondrial matrix
GO:0005886 plasma membrane
GO:0006633 fatty acid biosynthetic process
GO:0006703 estrogen biosynthetic process
GO:0008209 androgen metabolic process
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0044594 17-beta-hydroxysteroid dehydrogenase (NAD+) activity
GO:0046949 fatty-acyl-CoA biosynthetic process
GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity
GO:0047035 testosterone dehydrogenase (NAD+) activity
GO:0048038 quinone binding
GO:0051290 protein heterotetramerization
GO:0070404 NADH binding
GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR020904 Short-chain dehydrogenase/reductase, conserved siteSiteConserved site
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB03461 Nicotinamide adenine dinucleotide phosphateDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink