Entity Details

Primary name ENPP3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14638
EntryNameENPP3_HUMAN
FullNameEctonucleotide pyrophosphatase/phosphodiesterase family member 3
TaxID9606
Evidenceevidence at protein level
Length875
SequenceStatuscomplete
DateCreated2002-09-19
DateModified2021-06-02

Ontological Relatives

GenesENPP3

GO terms

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GOName
GO:0002276 basophil activation involved in immune response
GO:0003676 nucleic acid binding
GO:0004528 phosphodiesterase I activity
GO:0005509 calcium ion binding
GO:0006220 pyrimidine nucleotide metabolic process
GO:0006796 phosphate-containing compound metabolic process
GO:0008270 zinc ion binding
GO:0009143 nucleoside triphosphate catabolic process
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0033007 negative regulation of mast cell activation involved in immune response
GO:0035529 NADH pyrophosphatase activity
GO:0036218 dTTP diphosphatase activity
GO:0046034 ATP metabolic process
GO:0047429 nucleoside-triphosphate diphosphatase activity
GO:0048471 perinuclear region of cytoplasm
GO:0050728 negative regulation of inflammatory response
GO:0070062 extracellular exosome
GO:0070667 negative regulation of mast cell proliferation

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR001212 Somatomedin B domainDomainDomain
IPR001604 DNA/RNA non-specific endonucleaseDomainDomain
IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferaseFamilyFamily
IPR017850 Alkaline-phosphatase-like, core domain superfamilyFamilyHomologous superfamily
IPR020821 Extracellular Endonuclease, subunit ADomainDomain
IPR036024 Somatomedin B-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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