Entity Details

Primary name HMR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ95460
EntryNameHMR1_HUMAN
FullNameMajor histocompatibility complex class I-related gene protein
TaxID9606
Evidenceevidence at protein level
Length341
SequenceStatuscomplete
DateCreated2008-07-22
DateModified2021-06-02

Ontological Relatives

GenesMR1

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0002854 positive regulation of T cell mediated cytotoxicity directed against tumor cell target
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006955 immune response
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0019884 antigen processing and presentation of exogenous antigen
GO:0030881 beta-2-microglobulin binding
GO:0031901 early endosome membrane
GO:0031902 late endosome membrane
GO:0032393 MHC class I receptor activity
GO:0033077 T cell differentiation in thymus
GO:0042608 T cell receptor binding
GO:0042612 MHC class I protein complex
GO:0045087 innate immune response
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium

Subcellular Location

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Subcellular Location
Cell membrane
Early endosome membrane
Endoplasmic reticulum membrane
Golgi apparatus membrane
Late endosome membrane
Secreted

Domains

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DomainNameCategoryType
IPR001039 MHC class I alpha chain, alpha1 alpha2 domainsDomainDomain
IPR003006 Immunoglobulin/major histocompatibility complex, conserved siteSiteConserved site
IPR003597 Immunoglobulin C1-setDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR011161 MHC class I-like antigen recognition-likeDomainDomain
IPR011162 MHC classes I/II-like antigen recognition proteinFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR037055 MHC class I-like antigen recognition-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00098 Antithymocyte immunoglobulin (rabbit)Drugbankbiotech