Entity Details

Primary name DDX11_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96FC9
EntryNameDDX11_HUMAN
FullNameATP-dependent DNA helicase DDX11
TaxID9606
Evidenceevidence at protein level
Length970
SequenceStatuscomplete
DateCreated2006-01-10
DateModified2021-06-02

Ontological Relatives

GenesDDX11

GO terms

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GOName
GO:0000785 chromatin
GO:0000922 spindle pole
GO:0001650 fibrillar center
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0003688 DNA replication origin binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0003727 single-stranded RNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0006281 DNA repair
GO:0006974 cellular response to DNA damage stimulus
GO:0007062 sister chromatid cohesion
GO:0007275 multicellular organism development
GO:0008094 ATPase, acting on DNA
GO:0008186 ATPase, acting on RNA
GO:0016032 viral process
GO:0030496 midbody
GO:0031297 replication fork processing
GO:0032079 positive regulation of endodeoxyribonuclease activity
GO:0032091 negative regulation of protein binding
GO:0032508 DNA duplex unwinding
GO:0034085 establishment of sister chromatid cohesion
GO:0035563 positive regulation of chromatin binding
GO:0036498 IRE1-mediated unfolded protein response
GO:0044806 G-quadruplex DNA unwinding
GO:0045142 triplex DNA binding
GO:0045876 positive regulation of sister chromatid cohesion
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0051880 G-quadruplex DNA binding
GO:0070062 extracellular exosome
GO:0072711 cellular response to hydroxyurea
GO:0072719 cellular response to cisplatin
GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
GO:1904976 cellular response to bleomycin
GO:1990700 nucleolar chromatin organization
GO:2000781 positive regulation of double-strand break repair

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Midbody
Nucleus

Domains

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DomainNameCategoryType
IPR006554 Helicase-like, DEXD box c2 typeDomainDomain
IPR006555 ATP-dependent helicase, C-terminalDomainDomain
IPR010614 DEAD2DomainDomain
IPR013020 ATP-dependent helicase Rad3/Chl1-likeFamilyFamily
IPR014013 Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-typeDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR028331 ATP-dependent RNA helicase CHL1/DDX11FamilyFamily

Diseases

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