Entity Details

Primary name DHTK1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96HY7
EntryNameDHTK1_HUMAN
FullNameProbable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length919
SequenceStatuscomplete
DateCreated2007-10-23
DateModified2021-06-02

Ontological Relatives

GenesDHTKD1

GO terms

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GOName
GO:0002244 hematopoietic progenitor cell differentiation
GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006091 generation of precursor metabolites and energy
GO:0006096 glycolytic process
GO:0006099 tricarboxylic acid cycle
GO:0030976 thiamine pyrophosphate binding

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR001017 Dehydrogenase, E1 componentDomainDomain
IPR005475 Transketolase-like, pyrimidine-binding domainDomainDomain
IPR011603 2-oxoglutarate dehydrogenase E1 componentFamilyFamily
IPR029061 Thiamin diphosphate-binding foldFamilyHomologous superfamily
IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminalDomainDomain
IPR042179 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DHTK1_HUMANBMAL1_HUMANBioGRID, IntAct32296183 details