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Entity Details
Primary name
BIRC8_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q96P09
EntryName
BIRC8_HUMAN
FullName
Baculoviral IAP repeat-containing protein 8
TaxID
9606
Evidence
evidence at protein level
Length
236
SequenceStatus
complete
DateCreated
2002-07-11
DateModified
2021-06-02
Ontological Relatives
GO terms
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GO
Name
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005876
spindle microtubule
GO:0031398
positive regulation of protein ubiquitination
GO:0043027
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066
negative regulation of apoptotic process
GO:0046872
metal ion binding
GO:0051726
regulation of cell cycle
GO:0061630
ubiquitin protein ligase activity
GO:0090263
positive regulation of canonical Wnt signaling pathway
Subcellular Location
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Subcellular Location
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR001370
BIR repeat
Repeat
Repeat
IPR001841
Zinc finger, RING-type
Domain
Domain
IPR013083
Zinc finger, RING/FYVE/PHD-type
Family
Homologous superfamily
IPR042579
XIAP/BIRC8, UBA domain
Domain
Domain
Diseases
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Drugs
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Interactions
10 interactions
Interactor
Partner
Sources
Publications
Link
BIRC8_HUMAN
UB2D1_HUMAN
IntAct
19549727
details
BIRC8_HUMAN
UB2D2_HUMAN
IntAct
19549727
details
BIRC8_HUMAN
UB2D3_HUMAN
IntAct
19549727
details
BIRC8_HUMAN
UB2E1_HUMAN
IntAct
19549727
details
BIRC8_HUMAN
UBE2N_HUMAN
IntAct
19549727
details
BIRC8_HUMAN
UB2V1_HUMAN
IntAct
19549727
details
BIRC8_HUMAN
UB2D4_HUMAN
IntAct
19549727
details
BIRC8_HUMAN
UBE2W_HUMAN
IntAct
19549727
details
BIRC8_HUMAN
PKHN1_HUMAN
MINT
29433439
details
BIRC8_HUMAN
CASP9_HUMAN
HPRD, IntAct
11390657
28514442
details
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