Entity Details

Primary name CLC7A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BXN2
EntryNameCLC7A_HUMAN
FullNameC-type lectin domain family 7 member A
TaxID9606
Evidenceevidence at protein level
Length247
SequenceStatuscomplete
DateCreated2006-12-12
DateModified2021-06-02

Ontological Relatives

GenesCLEC7A

GO terms

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GOName
GO:0001872 (1->3)-beta-D-glucan binding
GO:0002366 leukocyte activation involved in immune response
GO:0002732 positive regulation of dendritic cell cytokine production
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006910 phagocytosis, recognition
GO:0006954 inflammatory response
GO:0008037 cell recognition
GO:0008284 positive regulation of cell population proliferation
GO:0009756 carbohydrate mediated signaling
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0016021 integral component of membrane
GO:0016046 detection of fungus
GO:0030246 carbohydrate binding
GO:0030335 positive regulation of cell migration
GO:0031334 positive regulation of protein-containing complex assembly
GO:0032491 detection of molecule of fungal origin
GO:0032729 positive regulation of interferon-gamma production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032733 positive regulation of interleukin-10 production
GO:0032735 positive regulation of interleukin-12 production
GO:0032743 positive regulation of interleukin-2 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032874 positive regulation of stress-activated MAPK cascade
GO:0032930 positive regulation of superoxide anion generation
GO:0038187 pattern recognition receptor activity
GO:0042110 T cell activation
GO:0042287 MHC protein binding
GO:0042802 identical protein binding
GO:0042832 defense response to protozoan
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045087 innate immune response
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0046872 metal ion binding
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050766 positive regulation of phagocytosis
GO:0051251 positive regulation of lymphocyte activation
GO:0051712 positive regulation of killing of cells of other organism
GO:0060267 positive regulation of respiratory burst
GO:0071226 cellular response to molecule of fungal origin
GO:0071639 positive regulation of monocyte chemotactic protein-1 production
GO:0090303 positive regulation of wound healing
GO:1900017 positive regulation of cytokine production involved in inflammatory response
GO:1903431 positive regulation of cell maturation

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR001304 C-type lectin-likeDomainDomain
IPR016186 C-type lectin-like/link domain superfamilyFamilyHomologous superfamily
IPR016187 C-type lectin foldFamilyHomologous superfamily
IPR033992 Natural killer cell receptor-like, C-type lectin-like domainDomainDomain
IPR042808 C-type lectin domain family 7 member AFamilyFamily

Diseases

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Interactions

52 interactions

InteractorPartnerSourcesPublicationsLink
CLC7A_HUMANSYNE4_HUMANBioGRID, IntAct, MINT21516116 25416956 details
CLC7A_HUMANBNI3L_HUMANBioGRID, IntAct, MINT21516116 25416956 32296183 details
CLC7A_HUMANCH60_HUMANBioGRID, IntAct21988832 details
CLC7A_HUMANAIP_HUMANBioGRID, IntAct21988832 details
CLC7A_HUMANRANB9_HUMANBioGRID, IntAct21988832 details
CLC7A_HUMANPTTG_HUMANBioGRID, IntAct25416956 32296183 details
CLC7A_HUMANILRL1_HUMANBioGRID, IntAct25416956 details
CLC7A_HUMANBNIP3_HUMANBioGRID, IntAct25416956 32296183 details
CLC7A_HUMANOCLN_HUMANBioGRID, IntAct25416956 details
CLC7A_HUMANKTN1_HUMANBioGRID, IntAct25416956 details
CLC7A_HUMANJAGN1_HUMANBioGRID, IntAct25416956 details
CLC7A_HUMANTMM79_HUMANBioGRID, IntAct25416956 31515488 32296183 details
CLC7A_HUMANADA33_HUMANBioGRID, IntAct25416956 32296183 details
CLC7A_HUMANSMIM3_HUMANBioGRID, IntAct25416956 32296183 details
CLC7A_HUMANTMPS4_HUMANBioGRID, IntAct25416956 details
CLC7A_HUMANNINJ2_HUMANBioGRID, IntAct25416956 details
CLC7A_HUMANCLC7A_HUMANBioGRID, IntAct25416956 32296183 details
CLC7A_HUMANZFPL1_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANOLFM4_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANCTXN3_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANSC22A_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANUPK2_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANSGCB_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANHG2A_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANOPRM_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANTMPS2_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANAR13B_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANCD53_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANSAR1A_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANCXB1_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANINGR2_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANNEMP1_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANFCGR1_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANSPIT1_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANFNDC9_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANTLCD4_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANCXCL9_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANNRAC_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANNKG2A_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANNSG2_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANASGR2_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANTEX29_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANSUSD3_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANVISTA_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANIF3M_HUMANBioGRID, IntAct32296183 details
CLC7A_HUMANCALM1_HUMANBioGRID25416956 details
CLC7A_HUMANCALM2_HUMANBioGRID25416956 details
CLC7A_HUMANCALM3_HUMANBioGRID25416956 details
CLC7A_HUMANFAM3A_HUMANBioGRID25416956 details
CLC7A_HUMANRHOU_HUMANBioGRID26598620 details
CLC7A_HUMANTLR2_HUMANBioGRID21899704 details
CLC7A_HUMANSOCS1_HUMANBioGRID21899704 29991678 details