Entity Details

Primary name TBL1R_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BZK7
EntryNameTBL1R_HUMAN
FullNameF-box-like/WD repeat-containing protein TBL1XR1
TaxID9606
Evidenceevidence at protein level
Length514
SequenceStatuscomplete
DateCreated2002-09-19
DateModified2021-06-02

Ontological Relatives

GenesTBL1XR1

GO terms

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GOName
GO:0000118 histone deacetylase complex
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0008013 beta-catenin binding
GO:0016575 histone deacetylation
GO:0017053 transcription repressor complex
GO:0019216 regulation of lipid metabolic process
GO:0030522 intracellular receptor signaling pathway
GO:0042393 histone binding
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0047485 protein N-terminus binding
GO:0072686 mitotic spindle
GO:0090263 positive regulation of canonical Wnt signaling pathway

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR006594 LIS1 homology motifDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR020472 G-protein beta WD-40 repeatRepeatRepeat
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

32 interactions

InteractorPartnerSourcesPublicationsLink
TBL1R_HUMANTBL1X_HUMANBioGRID, HPRD, IntAct15601853 18202150 18374649 21258344 27880911 details
TBL1R_HUMANNCOR1_HUMANBioGRID, HPRD, IntAct11931768 12628926 14527417 15601853 18202150 21258344 28152507 28348241 28588275 details
TBL1R_HUMANARL2_HUMANBioGRID, IntAct25416956 31515488 details
TBL1R_HUMANFOXK2_HUMANBioGRID, MINT25609649 27773593 details
TBL1R_HUMANMECP2_HUMANBioGRID, DIP23770565 28348241 details
TBL1R_HUMANATX1_HUMANBioGRID, IntAct, UniProt25959826 32814053 details
TBL1R_HUMANIDLC_HUMANIntAct32814053 details
TBL1R_HUMANKLF11_HUMANIntAct32814053 details
TBL1R_HUMANSODC_HUMANIntAct32814053 details
TBL1R_HUMANH4_HUMANBioGRID, HPRD12628926 15601853 30804502 details
TBL1R_HUMANH2B2E_HUMANBioGRID, HPRD12628926 15601853 details
TBL1R_HUMANUBC9_HUMANBioGRID26369384 details
TBL1R_HUMANOGT1_HUMANBioGRID32994395 details
TBL1R_HUMANHDAC3_HUMANBioGRID, HPRD, IntAct11931768 16469706 18202150 21258344 23752268 28152507 details
TBL1R_HUMANGPS2_HUMANBioGRID, HPRD, IntAct11931768 21258344 26186194 28514442 details
TBL1R_HUMANHDAC5_HUMANBioGRID, IntAct21081666 23752268 details
TBL1R_HUMANESR1_HUMANBioGRID, IntAct16469706 23403292 31527615 details
TBL1R_HUMANUB2E3_HUMANBioGRID18202150 details
TBL1R_HUMANEMD_HUMANBioGRID17620012 details
TBL1R_HUMANTHA_HUMANBioGRID17242407 details
TBL1R_HUMANTHB_HUMANBioGRID17242407 details
TBL1R_HUMANBCL3_HUMANBioGRID20547759 details
TBL1R_HUMANSOX2_HUMANBioGRID21532573 details
TBL1R_HUMANUB2D1_HUMANBioGRID14980219 details
TBL1R_HUMANCTNB1_HUMANBioGRID18193033 28588275 details
TBL1R_HUMANTAB2_HUMANBioGRID16469706 details
TBL1R_HUMANANDR_HUMANBioGRID16469706 32814769 details
TBL1R_HUMANRARA_HUMANBioGRID16469706 details
TBL1R_HUMANSIR6_HUMANBioGRID24169447 details
TBL1R_HUMANUBP44_HUMANBioGRID27880911 32076268 details
TBL1R_HUMANTULP3_HUMANBioGRID33187986 details
TBL1R_HUMANCOR2A_HUMANHPRD12628926 details