Entity Details

Primary name NVL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15381
EntryNameNVL_HUMAN
FullNameNuclear valosin-containing protein-like
TaxID9606
Evidenceevidence at protein level
Length856
SequenceStatuscomplete
DateCreated2003-07-11
DateModified2021-06-02

Ontological Relatives

GenesNVL

GO terms

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GOName
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005697 telomerase holoenzyme complex
GO:0005730 nucleolus
GO:0006364 rRNA processing
GO:0016020 membrane
GO:0016887 ATP hydrolysis activity
GO:0032092 positive regulation of protein binding
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:0051973 positive regulation of telomerase activity
GO:1904749 regulation of protein localization to nucleolus
GO:1990275 preribosome binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR003593 AAA+ ATPase domainDomainDomain
IPR003959 ATPase, AAA-type, coreDomainDomain
IPR003960 ATPase, AAA-type, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR031996 NVL2, nucleolin binding domainDomainDomain
IPR038100 NVL2, N-terminal domain superfamilyFamilyHomologous superfamily
IPR041569 AAA ATPase, AAA+ lid domainDomainDomain

Diseases

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