Entity Details

Primary name CP343_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HB55
EntryNameCP343_HUMAN
FullNameCytochrome P450 3A43
TaxID9606
Evidenceevidence at protein level
Length503
SequenceStatuscomplete
DateCreated2002-01-31
DateModified2021-06-02

Ontological Relatives

GenesCYP3A43

GO terms

Show/Hide Table
GOName
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0005789 endoplasmic reticulum membrane
GO:0008202 steroid metabolic process
GO:0008395 steroid hydroxylase activity
GO:0020037 heme binding
GO:0050649 testosterone 6-beta-hydroxylase activity
GO:0070330 aromatase activity
GO:0070989 oxidative demethylation
GO:0101020 estrogen 16-alpha-hydroxylase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Endoplasmic reticulum membrane
Microsome membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR001128 Cytochrome P450FamilyFamily
IPR002402 Cytochrome P450, E-class, group IIFamilyFamily
IPR008072 Cytochrome P450, E-class, CYP3AFamilyFamily
IPR017972 Cytochrome P450, conserved siteSiteConserved site
IPR036396 Cytochrome P450 superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00176 FluvoxamineDrugbanksmall molecule
DB00334 OlanzapineDrugbanksmall molecule
DB00409 RemoxiprideDrugbanksmall molecule
DB00593 EthosuximideDrugbanksmall molecule
DB00599 ThiopentalDrugbanksmall molecule
DB00624 TestosteroneDrugbanksmall molecule
DB00635 PrednisoneDrugbanksmall molecule
DB00643 MebendazoleDrugbanksmall molecule
DB00780 PhenelzineDrugbanksmall molecule
DB00959 MethylprednisoloneDrugbanksmall molecule
DB01045 RifampicinDrugbanksmall molecule
DB01058 PraziquantelSwissprotsmall molecule
DB01149 NefazodoneDrugbanksmall molecule
DB01201 RifapentineDrugbanksmall molecule
DB01222 BudesonideDrugbanksmall molecule
DB01234 DexamethasoneDrugbanksmall molecule
DB01601 LopinavirDrugbanksmall molecule
DB06412 OxymetholoneDrugbanksmall molecule
DB06448 LonafarnibDrugbanksmall molecule
DB06595 MidostaurinDrugbanksmall molecule
DB08865 CrizotinibDrugbanksmall molecule
DB08930 DolutegravirDrugbanksmall molecule
DB09048 NetupitantDrugbanksmall molecule
DB09054 IdelalisibDrugbanksmall molecule
DB09065 CobicistatSwissprotsmall molecule
DB09102 DaclatasvirDrugbanksmall molecule
DB09205 MoxisylyteDrugbanksmall molecule
DB09212 LoxoprofenDrugbanksmall molecule
DB09568 Omega-3-carboxylic acidsDrugbanksmall molecule
DB11574 ElbasvirDrugbanksmall molecule
DB11605 MyrrhDrugbanksmall molecule
DB11652 TucatinibDrugbanksmall molecule
DB11691 NaldemedineDrugbanksmall molecule
DB11703 AcalabrutinibDrugbanksmall molecule
DB11757 IstradefyllineDrugbanksmall molecule
DB11792 MirodenafilSwissprotsmall molecule
DB11853 RelugolixDrugbanksmall molecule
DB11951 LemborexantDrugbanksmall molecule
DB11979 ElagolixDrugbanksmall molecule
DB11994 DiacereinDrugbanksmall molecule
DB12070 LetermovirDrugbanksmall molecule
DB12130 LorlatinibDrugbanksmall molecule
DB12267 BrigatinibDrugbanksmall molecule
DB12307 ForetinibDrugbanksmall molecule
DB12332 RucaparibDrugbanksmall molecule
DB12887 TazemetostatDrugbanksmall molecule
DB13141 Ambroxol acefyllinateSwissprotsmall molecule
DB13174 RheinDrugbanksmall molecule
DB13179 TroleandomycinDrugbanksmall molecule
DB13878 PibrentasvirDrugbanksmall molecule
DB13879 GlecaprevirDrugbanksmall molecule
DB13943 Testosterone cypionateDrugbanksmall molecule
DB13944 Testosterone enanthateDrugbanksmall molecule
DB13946 Testosterone undecanoateDrugbanksmall molecule
DB14631 Prednisolone phosphateDrugbanksmall molecule
DB14649 Dexamethasone acetateDrugbanksmall molecule
DB15035 ZanubrutinibDrugbanksmall molecule
DB15305 RisdiplamSwissprotsmall molecule
DB15685 SelpercatinibDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink