Entity Details

Primary name VPP4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HBG4
EntryNameVPP4_HUMAN
FullNameV-type proton ATPase 116 kDa subunit a isoform 4
TaxID9606
Evidenceevidence at protein level
Length840
SequenceStatuscomplete
DateCreated2003-11-14
DateModified2021-06-02

Ontological Relatives

GenesATP6V0A4

GO terms

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GOName
GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain
GO:0001503 ossification
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0006885 regulation of pH
GO:0007035 vacuolar acidification
GO:0007588 excretion
GO:0007605 sensory perception of sound
GO:0008286 insulin receptor signaling pathway
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0016471 vacuolar proton-transporting V-type ATPase complex
GO:0030670 phagocytic vesicle membrane
GO:0031526 brush border membrane
GO:0033572 transferrin transport
GO:0034220 ion transmembrane transport
GO:0045177 apical part of cell
GO:0046961 proton-transporting ATPase activity, rotational mechanism
GO:0051117 ATPase binding
GO:0070062 extracellular exosome
GO:0090383 phagosome acidification
GO:1902600 proton transmembrane transport

Subcellular Location

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Subcellular Location
Apical cell membrane

Domains

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DomainNameCategoryType
IPR002490 V-type ATPase, V0 complex, 116kDa subunit familyFamilyFamily
IPR026028 ATPase, V0 complex, subunit 116kDa, eukaryoticFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01133 Tiludronic acidDrugbanksmall molecule

Interactions

5 interactions