Entity Details

Primary name CP26A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43174
EntryNameCP26A_HUMAN
FullNameCytochrome P450 26A1
TaxID9606
Evidenceevidence at protein level
Length497
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesCYP26A1

GO terms

Show/Hide Table
GOName
GO:0001822 kidney development
GO:0001972 retinoic acid binding
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0005789 endoplasmic reticulum membrane
GO:0006766 vitamin metabolic process
GO:0006805 xenobiotic metabolic process
GO:0008401 retinoic acid 4-hydroxylase activity
GO:0016125 sterol metabolic process
GO:0016491 oxidoreductase activity
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0032526 response to retinoic acid
GO:0033189 response to vitamin A
GO:0034653 retinoic acid catabolic process
GO:0042573 retinoic acid metabolic process
GO:0048387 negative regulation of retinoic acid receptor signaling pathway
GO:0062182 all-trans retinoic acid 4-hydrolase activity
GO:0062183 all-trans retinoic acid 18-hydroxylase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Endoplasmic reticulum membrane
Microsome membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR001128 Cytochrome P450FamilyFamily
IPR002403 Cytochrome P450, E-class, group IVFamilyFamily
IPR017972 Cytochrome P450, conserved siteSiteConserved site
IPR036396 Cytochrome P450 superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00162 Vitamin ADrugbanksmall molecule
DB00755 TretinoinDrugbanksmall molecule
DB13083 TalarozoleDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink