Entity Details

Primary name GRHL1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NZI5
EntryNameGRHL1_HUMAN
FullNameGrainyhead-like protein 1 homolog
TaxID9606
Evidenceevidence at protein level
Length618
SequenceStatuscomplete
DateCreated2006-03-21
DateModified2021-06-02

Ontological Relatives

GenesGRHL1

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002934 desmosome organization
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008544 epidermis development
GO:0019222 regulation of metabolic process
GO:0031490 chromatin DNA binding
GO:0042803 protein homodimerization activity
GO:0043231 intracellular membrane-bounded organelle
GO:0043565 sequence-specific DNA binding
GO:0045616 regulation of keratinocyte differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0061436 establishment of skin barrier
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR007604 CP2 transcription factorDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
GRHL1_HUMANGRHL3_HUMANBioGRID, HPRD12549979 details
GRHL1_HUMANGRHL1_HUMANHPRD10644752 details