Entity Details

Primary name ACHA9_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UGM1
EntryNameACHA9_HUMAN
FullNameNeuronal acetylcholine receptor subunit alpha-9
TaxID9606
Evidenceevidence at protein level
Length479
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesCHRNA9

GO terms

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GOName
GO:0004888 transmembrane signaling receptor activity
GO:0005262 calcium channel activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005892 acetylcholine-gated channel complex
GO:0007165 signal transduction
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007268 chemical synaptic transmission
GO:0022848 acetylcholine-gated cation-selective channel activity
GO:0030594 neurotransmitter receptor activity
GO:0034220 ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0042472 inner ear morphogenesis
GO:0043005 neuron projection
GO:0045202 synapse
GO:0050877 nervous system process
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0098981 cholinergic synapse
GO:0099060 integral component of postsynaptic specialization membrane

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR002394 Nicotinic acetylcholine receptorFamilyFamily
IPR006029 Neurotransmitter-gated ion-channel transmembrane domainDomainDomain
IPR006201 Neurotransmitter-gated ion-channelFamilyFamily
IPR006202 Neurotransmitter-gated ion-channel ligand-binding domainDomainDomain
IPR018000 Neurotransmitter-gated ion-channel, conserved siteSiteConserved site
IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamilyFamilyHomologous superfamily
IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00184 NicotineDrugbanksmall molecule
DB00237 ButabarbitalDrugbanksmall molecule
DB00898 EthanolDrugbanksmall molecule
DB05069 ATG003Drugbanksmall molecule
DB05137 LobelineDrugbanksmall molecule
DB05740 RPI-78MDrugbanksmall molecule
DB08837 TetraethylammoniumDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ACHA9_HUMANACHA9_HUMANDIP25282151 details