Entity Details

Primary name AGRE2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UHX3
EntryNameAGRE2_HUMAN
FullNameAdhesion G protein-coupled receptor E2
TaxID9606
Evidenceevidence at protein level
Length823
SequenceStatuscomplete
DateCreated2004-03-01
DateModified2021-06-02

Ontological Relatives

GenesADGRE2

GO terms

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GOName
GO:0004930 G protein-coupled receptor activity
GO:0005509 calcium ion binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006954 inflammatory response
GO:0007155 cell adhesion
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0016021 integral component of membrane
GO:0016477 cell migration
GO:0031256 leading edge membrane
GO:0032587 ruffle membrane
GO:0035374 chondroitin sulfate binding
GO:0043304 regulation of mast cell degranulation
GO:0071621 granulocyte chemotaxis

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000203 GPS motifDomainDomain
IPR000742 EGF-like domainDomainDomain
IPR000832 GPCR, family 2, secretin-likeFamilyFamily
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR003056 GPCR, family 2, ADGRE2/ADGRE5FamilyFamily
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR017983 GPCR, family 2, secretin-like, conserved siteSiteConserved site
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site

Diseases

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