Entity Details

Primary name ST14_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y5Y6
EntryNameST14_HUMAN
FullNameSuppressor of tumorigenicity 14 protein
TaxID9606
Evidenceevidence at protein level
Length855
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesST14

GO terms

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GOName
GO:0001843 neural tube closure
GO:0004252 serine-type endopeptidase activity
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006508 proteolysis
GO:0008236 serine-type peptidase activity
GO:0016323 basolateral plasma membrane
GO:0019897 extrinsic component of plasma membrane
GO:0030216 keratinocyte differentiation
GO:0060672 epithelial cell morphogenesis involved in placental branching
GO:0070268 cornification

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000082 SEA domainDomainDomain
IPR000859 CUB domainDomainDomain
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR002172 Low-density lipoprotein (LDL) receptor class A repeatRepeatRepeat
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR017051 Peptidase S1A, matripaseFamilyFamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved siteSiteConserved site
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR035914 Spermadhesin, CUB domain superfamilyFamilyHomologous superfamily
IPR036055 LDL receptor-like superfamilyFamilyHomologous superfamily
IPR036364 SEA domain superfamilyFamilyHomologous superfamily
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00013 UrokinaseDrugbankbiotech
DB03127 BenzamidineDrugbanksmall molecule
DB13729 CamostatDrugbanksmall molecule