Entity Details

Primary name EPN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95208
EntryNameEPN2_HUMAN
FullNameEpsin-2
TaxID9606
Evidenceevidence at protein level
Length641
SequenceStatuscomplete
DateCreated2004-01-16
DateModified2021-06-02

Ontological Relatives

GenesEPN2

GO terms

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GOName
GO:0005543 phospholipid binding
GO:0005768 endosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006897 endocytosis
GO:0030125 clathrin vesicle coat
GO:0030128 clathrin coat of endocytic vesicle
GO:0030276 clathrin binding
GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0043231 intracellular membrane-bounded organelle
GO:0045296 cadherin binding
GO:0045747 positive regulation of Notch signaling pathway
GO:0061024 membrane organization
GO:1903671 negative regulation of sprouting angiogenesis

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR003903 Ubiquitin interacting motifSiteConserved site
IPR008942 ENTH/VHSFamilyHomologous superfamily
IPR013809 ENTH domainDomainDomain
IPR027319 Epsin-2, metazoaFamilyFamily

Diseases

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Interactions

45 interactions

InteractorPartnerSourcesPublicationsLink
EPN2_HUMANDAZP2_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANPKHB2_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANTRI26_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANLITAF_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANCDIP1_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANRNF8_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANARRD3_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANARRD2_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANTHOP1_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANEIF3E_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANPMEPA_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANTRIM1_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANSMAD1_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANF168A_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANTXLNA_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANTRI62_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANWBP1_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANATX1_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANWBP2_HUMANBioGRID, IntAct27578003 32296183 details
EPN2_HUMANRL40_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANARRD1_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANFANCM_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANMAR1_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANLFG2_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANAAPK2_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANTRI18_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANTRI23_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANUBC_HUMANBioGRID, IntAct19285159 28190767 31699778 32296183 details
EPN2_HUMANSPART_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANPP4P1_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANWBP1L_HUMANBioGRID, IntAct32296183 details
EPN2_HUMANCLH1_HUMANBioGRID, HPRD10567358 details
EPN2_HUMANITSN1_HUMANBioGRID22558309 details
EPN2_HUMANAPOE_HUMANBioGRID21163940 details
EPN2_HUMANLAPM5_HUMANHPRD15231748 details
EPN2_HUMANRNF11_HUMANHPRD15231748 details
EPN2_HUMANRAB3I_HUMANBioGRID, IntAct27173435 unassigned1312 details
EPN2_HUMAN1433G_HUMANHPRD, IntAct15324660 28514442 details
EPN2_HUMANPICAL_HUMANIntAct31413325 details
EPN2_HUMANUBQL2_HUMANBioGRID18199683 details
EPN2_HUMANRBP1_HUMANBioGRID20709745 details
EPN2_HUMANSMAP2_HUMANBioGRID29395067 details
EPN2_HUMANAP2A_HUMANHPRD10567358 details
EPN2_HUMANEPS15_HUMANHPRD10567358 details
EPN2_HUMANTBA1B_HUMANHPRD12750376 details