Entity Details

Primary name G6PE_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95479
EntryNameG6PE_HUMAN
FullNameGDH/6PGL endoplasmic bifunctional protein
TaxID9606
Evidenceevidence at protein level
Length791
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesH6PD

GO terms

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GOName
GO:0004345 glucose-6-phosphate dehydrogenase activity
GO:0005739 mitochondrion
GO:0005788 endoplasmic reticulum lumen
GO:0006006 glucose metabolic process
GO:0009051 pentose-phosphate shunt, oxidative branch
GO:0017057 6-phosphogluconolactonase activity
GO:0030246 carbohydrate binding
GO:0047934 glucose 1-dehydrogenase (NAD+) activity
GO:0047935 glucose 1-dehydrogenase (NADP+) activity
GO:0050661 NADP binding
GO:0097305 response to alcohol
GO:2000064 regulation of cortisol biosynthetic process

Subcellular Location

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Subcellular Location
Endoplasmic reticulum lumen

Domains

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DomainNameCategoryType
IPR001282 Glucose-6-phosphate dehydrogenaseFamilyFamily
IPR005900 6-phosphogluconolactonase, DevB-typeDomainDomain
IPR006148 Glucosamine/galactosamine-6-phosphate isomeraseDomainDomain
IPR019796 Glucose-6-phosphate dehydrogenase, active siteSiteActive site
IPR022674 Glucose-6-phosphate dehydrogenase, NAD-bindingDomainDomain
IPR022675 Glucose-6-phosphate dehydrogenase, C-terminalDomainDomain
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily
IPR037171 NagB/RpiA transferase-likeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink