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Entity Details
Primary name
PGK1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P00558
EntryName
PGK1_HUMAN
FullName
Phosphoglycerate kinase 1
TaxID
9606
Evidence
evidence at protein level
Length
417
SequenceStatus
complete
DateCreated
1986-07-21
DateModified
2021-06-02
Ontological Relatives
Genes
PGK1
GO terms
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GO
Name
GO:0004618
phosphoglycerate kinase activity
GO:0005524
ATP binding
GO:0005615
extracellular space
GO:0005829
cytosol
GO:0006094
gluconeogenesis
GO:0006096
glycolytic process
GO:0016020
membrane
GO:0016310
phosphorylation
GO:0016525
negative regulation of angiogenesis
GO:0030855
epithelial cell differentiation
GO:0031639
plasminogen activation
GO:0043531
ADP binding
GO:0044003
modulation by symbiont of host process
GO:0045121
membrane raft
GO:0047134
protein-disulfide reductase (NAD(P)) activity
GO:0061621
canonical glycolysis
GO:0070062
extracellular exosome
GO:0071456
cellular response to hypoxia
Subcellular Location
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Subcellular Location
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR001576
Phosphoglycerate kinase
Family
Family
IPR015824
Phosphoglycerate kinase, N-terminal
Family
Homologous superfamily
IPR015911
Phosphoglycerate kinase, conserved site
Site
Conserved site
IPR036043
Phosphoglycerate kinase superfamily
Family
Homologous superfamily
Diseases
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Drugs
Show/Hide Table
Drug
Name
Source
Type
DB00709
Lamivudine
Drugbank
small molecule
DB00787
Acyclovir
Drugbank
small molecule
DB03909
Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate
Drugbank
small molecule
DB04510
3-phospho-D-glyceric acid
Drugbank
small molecule
DB09130
Copper
Drugbank
small molecule
DB11638
Artenimol
Drugbank
small molecule
Interactions
32 interactions
Interactor
Partner
Sources
Publications
Link
PGK1_HUMAN
DISC1_HUMAN
BioGRID, IntAct
17043677
31413325
details
PGK1_HUMAN
G3P_HUMAN
BioGRID, HPRD, MINT
20392205
22939629
26344197
8075252
9308888
details
PGK1_HUMAN
PCNA_HUMAN
BioGRID, MINT, UniProt
20849852
26030842
details
PGK1_HUMAN
HDAC3_HUMAN
DIP
26356530
details
PGK1_HUMAN
HS105_HUMAN
BioGRID, HPRD
14733918
details
PGK1_HUMAN
1433T_HUMAN
BioGRID
15161933
26344197
details
PGK1_HUMAN
RHOU_HUMAN
BioGRID
26598620
details
PGK1_HUMAN
BECN1_HUMAN
BioGRID
28238651
details
PGK1_HUMAN
NAA10_HUMAN
BioGRID
28238651
details
PGK1_HUMAN
CDC7_HUMAN
BioGRID
30392930
details
PGK1_HUMAN
CSK21_HUMAN
BioGRID
30392930
details
PGK1_HUMAN
PTEN_HUMAN
BioGRID
31492635
32249768
details
PGK1_HUMAN
SUMO2_HUMAN
BioGRID
24981860
32786267
details
PGK1_HUMAN
TBA1A_HUMAN
BioGRID
11444863
details
PGK1_HUMAN
UBE3A_HUMAN
BioGRID
31329371
details
PGK1_HUMAN
OGT1_HUMAN
BioGRID
32994395
details
PGK1_HUMAN
1433Z_HUMAN
BioGRID, MINT
15161933
26344197
details
PGK1_HUMAN
ELP3_HUMAN
DIP
26356530
details
PGK1_HUMAN
PMS1_HUMAN
BioGRID
17148452
details
PGK1_HUMAN
HDAC5_HUMAN
BioGRID
21081666
details
PGK1_HUMAN
ISG15_HUMAN
BioGRID
16009940
33024031
details
PGK1_HUMAN
HS90A_HUMAN
BioGRID
16263121
details
PGK1_HUMAN
MCM2_HUMAN
BioGRID
25963833
30392930
details
PGK1_HUMAN
U2AF2_HUMAN
BioGRID
26641092
details
PGK1_HUMAN
STAT3_HUMAN
BioGRID
23991099
details
PGK1_HUMAN
HIF1A_HUMAN
BioGRID, HPRD
23991099
8089148
details
PGK1_HUMAN
RFIP2_HUMAN
BioGRID
30471866
details
PGK1_HUMAN
PK3C3_HUMAN
BioGRID
28238651
details
PGK1_HUMAN
BAKOR_HUMAN
BioGRID
28238651
details
PGK1_HUMAN
TENA_HUMAN
BioGRID
21349332
details
PGK1_HUMAN
ATG5_HUMAN
BioGRID
33024031
details
PGK1_HUMAN
SUMO4_HUMAN
HPRD
16236267
details
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