Entity Details

Primary name IGHG3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP01860
EntryNameIGHG3_HUMAN
FullNameImmunoglobulin heavy constant gamma 3
TaxID9606
Evidenceevidence at protein level
Length377
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0001895 retina homeostasis
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0003823 antigen binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006910 phagocytosis, recognition
GO:0006911 phagocytosis, engulfment
GO:0006956 complement activation
GO:0006958 complement activation, classical pathway
GO:0008228 opsonization
GO:0009897 external side of plasma membrane
GO:0018149 peptide cross-linking
GO:0030449 regulation of complement activation
GO:0034987 immunoglobulin receptor binding
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0042571 immunoglobulin complex, circulating
GO:0042742 defense response to bacterium
GO:0045087 innate immune response
GO:0050853 B cell receptor signaling pathway
GO:0050871 positive regulation of B cell activation
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR003006 Immunoglobulin/major histocompatibility complex, conserved siteSiteConserved site
IPR003597 Immunoglobulin C1-setDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB15258 ImlifidaseDrugbankbiotech

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
IGHG3_HUMANNEMO_HUMANIntAct14743216 details