Entity Details

Primary name PPBT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP05186
EntryNamePPBT_HUMAN
FullNameAlkaline phosphatase, tissue-nonspecific isozyme
TaxID9606
Evidenceevidence at protein level
Length524
SequenceStatuscomplete
DateCreated1987-08-13
DateModified2021-06-02

Ontological Relatives

GenesALPL

GO terms

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GOName
GO:0001501 skeletal system development
GO:0001649 osteoblast differentiation
GO:0001958 endochondral ossification
GO:0003006 developmental process involved in reproduction
GO:0004035 alkaline phosphatase activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016311 dephosphorylation
GO:0016462 pyrophosphatase activity
GO:0031012 extracellular matrix
GO:0031225 anchored component of membrane
GO:0032496 response to lipopolysaccharide
GO:0033280 response to vitamin D
GO:0046677 response to antibiotic
GO:0046872 metal ion binding
GO:0051384 response to glucocorticoid
GO:0065010 extracellular membrane-bounded organelle
GO:0070062 extracellular exosome
GO:0071407 cellular response to organic cyclic compound
GO:0071529 cementum mineralization

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001952 Alkaline phosphataseFamilyFamily
IPR017850 Alkaline-phosphatase-like, core domain superfamilyFamilyHomologous superfamily
IPR018299 Alkaline phosphatase, active siteSiteActive site

Diseases

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Drugs

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DrugNameSourceType
DB00165 PyridoxineDrugbanksmall molecule
DB01143 AmifostineDrugbanksmall molecule
DB06716 FospropofolDrugbanksmall molecule
DB09338 MersalylDrugbanksmall molecule
DB09498 Strontium chloride Sr-89Swissprotsmall molecule