Entity Details

Primary name BGLR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP08236
EntryNameBGLR_HUMAN
FullNameBeta-glucuronidase
TaxID9606
Evidenceevidence at protein level
Length651
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesGUSB

GO terms

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GOName
GO:0004566 beta-glucuronidase activity
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005975 carbohydrate metabolic process
GO:0006027 glycosaminoglycan catabolic process
GO:0016020 membrane
GO:0019391 glucuronoside catabolic process
GO:0019904 protein domain specific binding
GO:0030214 hyaluronan catabolic process
GO:0030246 carbohydrate binding
GO:0035578 azurophil granule lumen
GO:0043202 lysosomal lumen
GO:0043231 intracellular membrane-bounded organelle
GO:0043312 neutrophil degranulation
GO:0070062 extracellular exosome
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Subcellular Location
Lysosome

Domains

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DomainNameCategoryType
IPR006101 Glycoside hydrolase, family 2FamilyFamily
IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwichDomainDomain
IPR006103 Glycoside hydrolase family 2, catalytic domainDomainDomain
IPR006104 Glycosyl hydrolases family 2, sugar binding domainDomainDomain
IPR008979 Galactose-binding-like domain superfamilyFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR017853 Glycoside hydrolase superfamilyFamilyHomologous superfamily
IPR023230 Glycoside hydrolase, family 2, conserved siteSiteConserved site
IPR023232 Glycoside hydrolase, family 2, active siteSiteActive site
IPR036156 Beta-Galactosidase/glucuronidase domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB09301 Chondroitin sulfateDrugbanksmall molecule
DB09340 Tyropanoic acidSwissprotsmall molecule
DB11793 NiraparibDrugbanksmall molecule

Interactions

4 interactions