Entity Details

Primary name DCOR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP11926
EntryNameDCOR_HUMAN
FullNameOrnithine decarboxylase
TaxID9606
Evidenceevidence at protein level
Length461
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesODC1

GO terms

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GOName
GO:0004586 ornithine decarboxylase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006521 regulation of cellular amino acid metabolic process
GO:0006595 polyamine metabolic process
GO:0009615 response to virus
GO:0033387 putrescine biosynthetic process from ornithine
GO:0042176 regulation of protein catabolic process
GO:0042803 protein homodimerization activity
GO:0048471 perinuclear region of cytoplasm

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000183 Ornithine/DAP/Arg decarboxylaseFamilyFamily
IPR002433 Ornithine decarboxylaseFamilyFamily
IPR009006 Alanine racemase/group IV decarboxylase, C-terminalFamilyHomologous superfamily
IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminalDomainDomain
IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminalDomainDomain
IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding siteSiteBinding site
IPR022657 Orn/DAP/Arg decarboxylase 2, conserved siteSiteConserved site
IPR029066 PLP-binding barrelFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00114 Pyridoxal phosphateDrugbanksmall molecule
DB00127 SpermineDrugbanksmall molecule
DB01917 PutrescineDrugbanksmall molecule
DB02209 Pyridoxine phosphateDrugbanksmall molecule
DB02824 N-Pyridoxyl-Glycine-5-MonophosphateDrugbanksmall molecule
DB03856 L-EflornithineDrugbanksmall molecule
DB04083 N(6)-(pyridoxal phosphate)-L-lysineDrugbanksmall molecule
DB04263 GeneticinDrugbanksmall molecule
DB06243 EflornithineDrugbanksmall molecule