Entity Details

Primary name KCRB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP12277
EntryNameKCRB_HUMAN
FullNameCreatine kinase B-type
TaxID9606
Evidenceevidence at protein level
Length381
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesCKB

GO terms

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GOName
GO:0004111 creatine kinase activity
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005829 cytosol
GO:0006600 creatine metabolic process
GO:0016301 kinase activity
GO:0021549 cerebellum development
GO:0021762 substantia nigra development
GO:0030425 dendrite
GO:0030644 cellular chloride ion homeostasis
GO:0031625 ubiquitin protein ligase binding
GO:0043025 neuronal cell body
GO:0046314 phosphocreatine biosynthetic process
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000749 ATP:guanido phosphotransferaseFamilyFamily
IPR014746 Glutamine synthetase/guanido kinase, catalytic domainFamilyHomologous superfamily
IPR022413 ATP:guanido phosphotransferase, N-terminalDomainDomain
IPR022414 ATP:guanido phosphotransferase, catalytic domainDomainDomain
IPR022415 ATP:guanido phosphotransferase active siteSiteActive site
IPR036802 ATP:guanido phosphotransferase, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00148 CreatineDrugbanksmall molecule
DB00300 Tenofovir disoproxilDrugbanksmall molecule
DB00787 AcyclovirDrugbanksmall molecule
DB13191 PhosphocreatineDrugbanksmall molecule
DB13749 Magnesium gluconateSwissprotsmall molecule