Entity Details

Primary name CBPB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15086
EntryNameCBPB1_HUMAN
FullNameCarboxypeptidase B
TaxID9606
Evidenceevidence at protein level
Length417
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesCPB1

GO terms

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GOName
GO:0004180 carboxypeptidase activity
GO:0004181 metallocarboxypeptidase activity
GO:0005615 extracellular space
GO:0006508 proteolysis
GO:0008270 zinc ion binding

Subcellular Location

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Subcellular Location
Secreted
Zymogen granule lumen

Domains

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DomainNameCategoryType
IPR000834 Peptidase M14, carboxypeptidase ADomainDomain
IPR003146 Carboxypeptidase, activation peptideDomainDomain
IPR034253 Carboxypeptidase B, carboxypeptidase domainDomainDomain
IPR036990 Metallocarboxypeptidase-like, propeptideFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04272 Citric acidDrugbanksmall molecule
DB04723 2-(3-GUANIDINOPHENYL)-3-MERCAPTOPROPANOIC ACIDDrugbanksmall molecule
DB06835 (2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(S)-HYDROXY[(1R)-2-METHYL-1-{[(2-PHENYLETHYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACIDDrugbanksmall molecule
DB06921 (2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL]PROPANOIC ACIDDrugbanksmall molecule
DB07136 BX-528Drugbanksmall molecule
DB07157 (5R,6S,8S)-8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDEDrugbanksmall molecule
DB07182 (2S)-2-(3-Carbamimidamidophenyl)-3-[hydroxy(3-phenylpropyl)phosphoryl]propanoic acidDrugbanksmall molecule
DB07269 (2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-METHYLPROPYL](HYDROXY)PHOSPHORYL]PROPANOIC ACIDDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CBPB1_HUMANA4_HUMANIntAct32814053 details