Entity Details

Primary name FABP4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15090
EntryNameFABP4_HUMAN
FullNameFatty acid-binding protein, adipocyte
TaxID9606
Evidenceevidence at protein level
Length132
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesFABP4

GO terms

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GOName
GO:0005324 long-chain fatty acid transporter activity
GO:0005504 fatty acid binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005811 lipid droplet
GO:0005829 cytosol
GO:0006469 negative regulation of protein kinase activity
GO:0009617 response to bacterium
GO:0015909 long-chain fatty acid transport
GO:0019433 triglyceride catabolic process
GO:0036041 long-chain fatty acid binding
GO:0042632 cholesterol homeostasis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0050729 positive regulation of inflammatory response
GO:0050872 white fat cell differentiation
GO:0050873 brown fat cell differentiation
GO:0051427 hormone receptor binding
GO:0070062 extracellular exosome
GO:0071285 cellular response to lithium ion
GO:0071356 cellular response to tumor necrosis factor
GO:0120162 positive regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000463 Cytosolic fatty-acid bindingDomainDomain
IPR000566 Lipocalin/cytosolic fatty-acid binding domainDomainDomain
IPR012674 CalycinFamilyHomologous superfamily
IPR031259 Intracellular lipid binding proteinFamilyFamily
IPR033073 Fatty acid-binding protein 4FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB02153 3-sulfino-L-alanineDrugbanksmall molecule
DB02776 1-Hexadecanosulfonic AcidDrugbanksmall molecule
DB03009 2-{[2-Oxo-2-(1-piperidinyl)ethyl]sulfanyl}-6-(trifluoromethyl)-4(1H)-pyrimidinoneSwissprotsmall molecule
DB03766 Propanoic acidDrugbanksmall molecule
DB03796 Palmitic AcidDrugbanksmall molecule
DB03851 Carbazole Butanoic AcidSwissprotsmall molecule
DB04224 Oleic AcidDrugbanksmall molecule
DB04437 Cysteine-Methylene-Carbamoyl-1,10-PhenanthrolineSwissprotsmall molecule
DB04474 8-anilinonaphthalene-1-sulfonic acidDrugbanksmall molecule
DB04557 Arachidonic AcidDrugbanksmall molecule
DB07283 9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acidSwissprotsmall molecule
DB07945 5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acidSwissprotsmall molecule
DB08607 (5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONEDrugbanksmall molecule