Entity Details

Primary name LFA3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP19256
EntryNameLFA3_HUMAN
FullNameLymphocyte function-associated antigen 3
TaxID9606
Evidenceevidence at protein level
Length250
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesCD58

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0030667 secretory granule membrane
GO:0032757 positive regulation of interleukin-8 production
GO:0034113 heterotypic cell-cell adhesion
GO:0043312 neutrophil degranulation
GO:0050900 leukocyte migration
GO:0070062 extracellular exosome
GO:0071346 cellular response to interferon-gamma
GO:0071356 cellular response to tumor necrosis factor
GO:0098609 cell-cell adhesion
GO:0101003 ficolin-1-rich granule membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015714 Lymphocyte function associated antigen 3FamilyFamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
LFA3_HUMANDNJA1_HUMANBioGRID, HPRD, IntAct16169070 details
LFA3_HUMANHERP1_HUMANBioGRID, HPRD, IntAct16169070 details
LFA3_HUMANPARP2_HUMANMINT21812934 details
LFA3_HUMANCD2_HUMANBioGRID, HPRD, IntAct11575926 1377404 21982860 details
LFA3_HUMANA4_HUMANBioGRID21832049 details