Entity Details

Primary name FPR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP21462
EntryNameFPR1_HUMAN
FullNamefMet-Leu-Phe receptor
TaxID9606
Evidenceevidence at protein level
Length350
SequenceStatuscomplete
DateCreated1991-05-01
DateModified2021-06-02

Ontological Relatives

GenesFPR1

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001664 G protein-coupled receptor binding
GO:0002430 complement receptor mediated signaling pathway
GO:0004875 complement receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0004982 N-formyl peptide receptor activity
GO:0005124 scavenger receptor binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007263 nitric oxide mediated signal transduction
GO:0016021 integral component of membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0030667 secretory granule membrane
GO:0035577 azurophil granule membrane
GO:0043312 neutrophil degranulation
GO:0050786 RAGE receptor binding
GO:0101003 ficolin-1-rich granule membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000826 Formyl peptide receptor-relatedFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain
IPR027345 Formyl peptide receptor 1/2FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00716 NedocromilDrugbanksmall molecule