Entity Details

Primary name ECHM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30084
EntryNameECHM_HUMAN
FullNameEnoyl-CoA hydratase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length290
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesECHS1

GO terms

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GOName
GO:0004300 enoyl-CoA hydratase activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006635 fatty acid beta-oxidation
GO:0009083 branched-chain amino acid catabolic process
GO:0043956 3-hydroxypropionyl-CoA dehydratase activity
GO:0120092 crotonyl-CoA hydratase activity

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR001753 Enoyl-CoA hydratase/isomeraseFamilyFamily
IPR014748 Enoyl-CoA hydratase, C-terminalFamilyHomologous superfamily
IPR018376 Enoyl-CoA hydratase/isomerase, conserved siteSiteConserved site
IPR029045 ClpP/crotonase-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02563 Hexanoyl-CoADrugbanksmall molecule
DB02910 Octanoyl-Coenzyme ADrugbanksmall molecule
DB03059 Acetoacetyl-CoADrugbanksmall molecule
DB04117 4-(N,N-Dimethylamino)cinnamoyl-CoADrugbanksmall molecule
DB09568 Omega-3-carboxylic acidsDrugbanksmall molecule

Interactions

42 interactions

InteractorPartnerSourcesPublicationsLink
ECHM_HUMANCBWD2_HUMANBioGRID, HPRD, IntAct16169070 details
ECHM_HUMANTRI63_HUMANMINT18157088 details
ECHM_HUMANSMUF2_HUMANMINT18157088 details
ECHM_HUMANGRB2_HUMANBioGRID, IntAct18624398 details
ECHM_HUMANCP2E1_HUMANBioGRID, IntAct21988832 details
ECHM_HUMANPPM1B_HUMANBioGRID, IntAct21988832 details
ECHM_HUMANUBA1_HUMANBioGRID, IntAct21988832 details
ECHM_HUMANCLD12_HUMANBioGRID, IntAct21988832 details
ECHM_HUMANECHM_HUMANBioGRID, IntAct21988832 details
ECHM_HUMANA1AT_HUMANBioGRID, IntAct21988832 details
ECHM_HUMANSTAT3_HUMANMINT23416296 details
ECHM_HUMANLRRK2_HUMANBioGRID, IntAct24510904 24947832 31046837 details
ECHM_HUMANLRRK1_HUMANBioGRID, IntAct24947832 29513927 details
ECHM_HUMANSAV1_HUMANIntAct22570112 details
ECHM_HUMANCAN1_HUMANBioGRID, HPRD12358155 22863883 details
ECHM_HUMANERPG3_HUMANBioGRID31722399 details
ECHM_HUMANERCC6_HUMANBioGRID31722399 details
ECHM_HUMANCDC42_HUMANBioGRID31478661 details
ECHM_HUMANTRAF6_HUMANIntAct17353931 details
ECHM_HUMANEIF1B_HUMANIntAct17353931 details
ECHM_HUMANRIPK2_HUMANIntAct17353931 details
ECHM_HUMANTFE3_HUMANIntAct17353931 details
ECHM_HUMANVHL_HUMANIntAct17353931 details
ECHM_HUMANTNIK_HUMANIntAct17353931 details
ECHM_HUMANGBRL2_HUMANIntAct17353931 details
ECHM_HUMANPAK2_HUMANIntAct17353931 details
ECHM_HUMANATG5_HUMANIntAct17353931 details
ECHM_HUMANCRCM_HUMANIntAct17353931 details
ECHM_HUMANTRM7_HUMANIntAct17353931 details
ECHM_HUMANIKKE_HUMANIntAct17353931 details
ECHM_HUMANAAKB1_HUMANIntAct17353931 details
ECHM_HUMANTIMP2_HUMANIntAct17353931 details
ECHM_HUMANHLAB_HUMANIntAct17353931 details
ECHM_HUMANSOMA_HUMANIntAct17353931 details
ECHM_HUMAN1433Z_HUMANBioGRID, MINT15161933 22863883 details
ECHM_HUMANYPEL5_HUMANBioGRID, IntAct27173435 unassigned1312 details
ECHM_HUMANPA2G4_HUMANBioGRID, IntAct27173435 unassigned1312 details
ECHM_HUMANUBE2N_HUMANBioGRID, IntAct27173435 unassigned1312 details
ECHM_HUMANTRAP1_HUMANBioGRID, IntAct27173435 31536960 34079125 unassigned1312 details
ECHM_HUMANSND1_HUMANBioGRID, IntAct27173435 unassigned1312 details
ECHM_HUMANFXR1_HUMANMINT21653829 details
ECHM_HUMANFXR2_HUMANMINT21653829 details