Entity Details

Primary name TNFL8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP32971
EntryNameTNFL8_HUMAN
FullNameTumor necrosis factor ligand superfamily member 8
TaxID9606
Evidenceevidence at protein level
Length234
SequenceStatuscomplete
DateCreated1993-10-01
DateModified2021-06-02

Ontological Relatives

GenesTNFSF8

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005125 cytokine activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007267 cell-cell signaling
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0042129 regulation of T cell proliferation
GO:0043374 CD8-positive, alpha-beta T cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050830 defense response to Gram-positive bacterium

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR006052 Tumour necrosis factor domainDomainDomain
IPR008983 Tumour necrosis factor-like domain superfamilyFamilyHomologous superfamily
IPR021184 Tumour necrosis factor, conserved siteSiteConserved site
IPR021185 Tumour necrosis factor family protein, CD30 ligand typeFamilyFamily

Diseases

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Interactions

4 interactions