Entity Details

Primary name IDUA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35475
EntryNameIDUA_HUMAN
FullNameAlpha-L-iduronidase
TaxID9606
Evidenceevidence at protein level
Length653
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesIDUA

GO terms

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GOName
GO:0003940 L-iduronidase activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0005102 signaling receptor binding
GO:0005984 disaccharide metabolic process
GO:0006027 glycosaminoglycan catabolic process
GO:0030135 coated vesicle
GO:0030207 chondroitin sulfate catabolic process
GO:0030209 dermatan sulfate catabolic process
GO:0030211 heparin catabolic process
GO:0043202 lysosomal lumen
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Lysosome

Domains

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DomainNameCategoryType
IPR000514 Glycoside hydrolase, family 39FamilyFamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR017853 Glycoside hydrolase superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB09301 Chondroitin sulfateDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
IDUA_HUMANMPP3_HUMANHPRD, IntAct16169070 details