Entity Details

Primary name NNMT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP40261
EntryNameNNMT_HUMAN
FullNameNicotinamide N-methyltransferase
TaxID9606
Evidenceevidence at protein level
Length264
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesNNMT

GO terms

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GOName
GO:0005829 cytosol
GO:0008112 nicotinamide N-methyltransferase activity
GO:0008170 N-methyltransferase activity
GO:0010243 response to organonitrogen compound
GO:0031100 animal organ regeneration
GO:0032259 methylation
GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway
GO:0042493 response to drug

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000940 Methyltransferase, NNMT/PNMT/TEMTFamilyFamily
IPR025820 Methyltransferase NNMT/PNMT/TEMT, conserved siteSiteConserved site
IPR029063 S-adenosyl-L-methionine-dependent methyltransferaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00627 NiacinDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
NNMT_HUMANATF6A_HUMANBioGRID, IntAct21988832 details
NNMT_HUMANBMF_HUMANBioGRID, IntAct21988832 details
NNMT_HUMANA4_HUMANBioGRID21832049 details